Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LANCL2 | Q9NS86 | 1/20 | 0.64 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17706597 | 0.89 | LANCL2 (0.78) | LANCL2HRH4GPR119PDE10APARP1 | |
| SCHEMBL29063389 | 0.89 | LANCL2 (0.80) | LANCL2HRH4PDE10AHRH3 | |
| SCHEMBL25311738 | 0.89 | LANCL2 (0.80) | LANCL2HRH4PDE10AHRH3 | |
| SCHEMBL29466328 | 0.89 | LANCL2 (0.80) | LANCL2HRH4PDE10AHRH3 | |
| SCHEMBL25877698 | 0.86 | LANCL2 (0.71) | LANCL2HRH4PDE10AHRH3 | |
| SCHEMBL25879427 | 0.86 | LANCL2 (0.69) | LANCL2HRH4GPR119PDE10APARP1 | |
| SCHEMBL25881623 | 0.85 | LANCL2 (0.64) | LANCL2GPR119PARP1SPR | |
| SCHEMBL25881549 | 0.84 | LANCL2 (0.66) | LANCL2HRH4GPR119PARP1SPR | |
| SCHEMBL25879553 | 0.84 | LANCL2 (0.60) | LANCL2HRH4PDE10APARP1HRH3 | |
| SCHEMBL25314522 | 0.83 | LANCL2 (0.70) | LANCL2HRH4PDE10AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |