⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2600733 | 0.75 | — | — | |
| SCHEMBL14818688 | 0.71 | — | — | |
| SCHEMBL9832575 | 0.70 | — | — | |
| SCHEMBL9124822 | 0.70 | ALDH1A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL9833404 | 0.68 | — | — | |
| SCHEMBL8737483 | 0.68 | — | — | |
| SCHEMBL4039336 | 0.67 | POLB (0.30) | — | |
| SCHEMBL12904544 | 0.64 | — | — | |
| SCHEMBL9832324 | 0.64 | JAK3 (0.33) | — | |
| SCHEMBL16248177 | 0.63 | GABRA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227474-A1 | COMPOSITIONS AND METHODS FOR CORRECTION OF ABERRANT SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2023-07-20 | — | — | US | disclosed |