Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 12/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30512112 | 0.78 | MAP3K5 (0.54) | MAP3K5BRAFROCK1 | |
| SCHEMBL25879550 | 0.78 | MAP3K5 (0.54) | MAP3K5BRAFROCK1 | |
| SCHEMBL30512115 | 0.72 | MAP3K5 (0.66) | MAP3K5BRAF | |
| SCHEMBL25881301 | 0.72 | MAP3K5 (0.66) | MAP3K5BRAF | |
| SCHEMBL25880122 | 0.72 | BRAF (0.64) | MAP3K5BRAF | |
| SCHEMBL6467426 | 0.71 | MAP3K5 (0.54) | MAP3K5FDPSROCK1ACVR1SMN1; SMN2 | |
| SCHEMBL830110 | 0.70 | ROCK1 (0.46) | MAP3K5FDPSROCK1ACVR1SMN1; SMN2 | |
| SCHEMBL30309907 | 0.70 | PLK1 (0.43) | MAP3K5FDPSSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL14842833 | 0.69 | PLK1 (0.42) | MAP3K5FDPSSMN1; SMN2 | |
| SCHEMBL30512136 | 0.68 | MAP3K5 (0.54) | MAP3K5BRAFFDPSROCK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138412-A1 | FUSED PYRIMIDIN-2-AMINE COMPOUNDS AS CDK20 INHIBITORS | INSILICO MEDICINE IP LIMITED (CN) | 2023-07-27 | — | — | WO | disclosed |