SCHEMBL25880531

SCHEMBL25880531

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)c3c(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)ccc5c3n4c3ccc(-c4nc(-c6ccccc6)nc(-c6ccccc6)n4)c4c6cc(-c7nc(-c8ccccc8)nc(-c8ccccc8)n7)ccc6n5c43)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
HPGD P15428 3/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
NTSR1 P30989 1/20 0.34
LMNA P02545 3/20 0.34
ADORA2A P29274 3/20 0.34
ADORA1 P30542 3/20 0.34
ADORA3 P0DMS8 2/20 0.34
ADORA2B P29275 2/20 0.34
POLB P06746 2/20 0.34
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
KDM4E B2RXH2 2/20 0.33
ATM Q13315 1/20 0.33
GLA P06280 1/20 0.33
ACP1 P24666 2/20 0.33
NR3C1 P04150 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25880522 0.88 ACP1 (0.37) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL25880521 0.84 KMT2A (0.37) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL25881217 0.83 MEN1 (0.33) MEN1KMT2AMAPTLMNAADORA2A
SCHEMBL24601527 0.82 MEN1 (0.39) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL24601529 0.82 MEN1 (0.39) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL11926479 0.81 MEN1 (0.40) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL16621688 0.79 MEN1 (0.39) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL21276424 0.78 MEN1 (0.38) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL21276423 0.78 MEN1 (0.38) MEN1KMT2AHPGDALDH1A1MAPT
SCHEMBL25880422 0.78 ALK (0.35) MEN1KMT2AMAPTL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240135-A1 HETEROCYLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, LAGE3, NQO1 MEN1 249/4885KMT2A 652/4885HPGD 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.