Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25255179 | 0.81 | NAMPT (0.43) | CYP4F2CYP4A11NAMPT | |
| SCHEMBL9454814 | 0.78 | RECQL (0.43) | RECQLCYP4F2CYP4A11LOXL2ROCK2 | |
| SCHEMBL25202974 | 0.78 | LOXL2 (0.53) | CYP4F2CYP4A11LOXL2ROCK2PKM | |
| Hydrochloric Acid SCHEMBL25233438 | 0.76 | LOXL2 (0.51) | CYP4F2CYP4A11LOXL2ROCK2PKM | |
| SCHEMBL30398877 | 0.76 | NAMPT (0.41) | GSK3BNAMPTVHLNPC1ALDH1A1 | |
| SCHEMBL25613777 | 0.76 | NAMPT (0.41) | GSK3BNAMPTVHLNPC1ALDH1A1 | |
| SCHEMBL25301777 | 0.74 | EPHX1 (0.43) | GSK3BNAMPTVHLSMN1; SMN2RAB9A | |
| SCHEMBL25301775 | 0.74 | EPHX1 (0.43) | GSK3BNAMPTVHLSMN1; SMN2RAB9A | |
| SCHEMBL31286041 | 0.71 | RECQL (0.50) | RECQLCYP2C9CYP2C19NAMPTSMN1; SMN2 | |
| SCHEMBL25613407 | 0.71 | GABRP (0.57) | RECQLCYP2C9CYP2C19ROCK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121992-A1 | CYCLOPROPYL COMPOUNDS | ICAGEN, LLC (US) | 2023-06-29 | — | — | WO | disclosed |