Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 5/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.38 |
| ▸ | LOX | P28300 | 5/20 | 0.38 |
| ▸ | PTGES | O14684 | 3/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174780 | 0.90 | RECQL (0.40) | RECQLCYP2C9CYP2C19ACACBLOXL2 | |
| SCHEMBL25639248 | 0.90 | RECQL (0.40) | RECQLCYP2C9CYP2C19ACACBLOXL2 | |
| SCHEMBL25880976 | 0.88 | RECQL (0.39) | RECQLCYP2C9CYP2C19ACACBLOXL2 | |
| SCHEMBL25880968 | 0.85 | RECQL (0.42) | RECQLCYP2C9CYP2C19LOXL2LOX | |
| SCHEMBL22324220 | 0.81 | EPHX2 (0.45) | RECQLCYP2C9CYP2C19LOXL2LOX | |
| SCHEMBL30569972 | 0.81 | EPHX2 (0.45) | RECQLCYP2C9CYP2C19LOXL2LOX | |
| SCHEMBL25880602 | 0.80 | LOX (0.57) | RECQLCYP2C9CYP2C19LOXL2LOX | |
| SCHEMBL25880800 | 0.80 | RECQL (0.42) | RECQLCYP2C9CYP2C19LOXL2LOX | |
| SCHEMBL25880555 | 0.80 | KLKB1 (0.46) | RECQLCYP2C9CYP2C19ACACBLOXL2 | |
| SCHEMBL25639296 | 0.79 | ACACB (0.35) | ACACBLOXL2LOXPTGESEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121992-A1 | CYCLOPROPYL COMPOUNDS | ICAGEN, LLC (US) | 2023-06-29 | — | — | WO | disclosed |