Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25971673 | 0.93 | DNM1 (0.39) | EPHX2CA1 | |
| SCHEMBL22986115 | 0.88 | CA1 (0.32) | CA1 | |
| SCHEMBL22509628 | 0.88 | KDM4C (0.33) | CA1 | |
| SCHEMBL25971286 | 0.86 | KDM4C (0.35) | CA1 | |
| SCHEMBL21868829 | 0.85 | KDM4C (0.31) | — | |
| SCHEMBL29300277 | 0.84 | EPHX2 (0.36) | EPHX2 | |
| SCHEMBL18948978 | 0.84 | ALDH1A1 (0.35) | CA1 | |
| SCHEMBL26049439 | 0.83 | DNM1 (0.32) | EPHX2 | |
| SCHEMBL25110743 | 0.81 | — | — | |
| SCHEMBL22986134 | 0.81 | DNM1 (0.34) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11707457-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11707457-B2 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | EPHX2 1890/4885CA1 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.