Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25876704 | 0.79 | IDO1 (0.44) | IDO1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL25876836 | 0.79 | IDO1 (0.44) | IDO1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL22043300 | 0.71 | CYP1A2 (0.42) | KDM4EALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL14103296 | 0.69 | IDO1 (0.38) | IDO1KDM4EUSP2ALDH1A1POLB | |
| SCHEMBL25885056 | 0.67 | CYP3A4 (0.36) | IDO1KDM4EALDH1A1POLBHPGD | |
| SCHEMBL9778189 | 0.66 | IDO1 (0.73) | IDO1KDM4EUSP2ALDH1A1POLB | |
| SCHEMBL30336868 | 0.66 | IDO1 (0.73) | IDO1KDM4EUSP2ALDH1A1POLB | |
| SCHEMBL2522240 | 0.65 | ALDH1A1 (0.41) | IDO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29419432 | 0.62 | CYP2A6 (0.40) | IDO1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29449705 | 0.62 | POLB (0.60) | IDO1KDM4EUSP2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |