Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26004528 | 0.76 | IDO1 (0.45) | IDO1MAPTTDP1KDM4EUSP2 | |
| SCHEMBL14023489 | 0.72 | IDO1 (0.43) | IDO1MAPTKDM4EUSP2MEN1 | |
| SCHEMBL19835498 | 0.71 | IDO1 (0.36) | IDO1USP2MEN1KMT2AKEAP1 | |
| SCHEMBL22620058 | 0.71 | IDO1 (0.48) | IDO1MAPTKDM4ERECQLALDH1A1 | |
| SCHEMBL8147899 | 0.70 | IDO1 (0.58) | IDO1MAPTTDP1KDM4EUSP2 | |
| SCHEMBL26144812 | 0.70 | ALDH1A1 (0.32) | KEAP1ALDH1A1HPGDHSD17B10NFE2L2 | |
| SCHEMBL25884154 | 0.69 | IDO1 (0.39) | IDO1MAPTTDP1KDM4EUSP2 | |
| SCHEMBL16194590 | 0.69 | HSD17B10 (0.48) | IDO1MAPTTDP1KDM4EUSP2 | |
| SCHEMBL2522240 | 0.69 | ALDH1A1 (0.41) | IDO1TDP1KDM4EKEAP1ALDH1A1 | |
| SCHEMBL28299700 | 0.68 | CYP2A6 (0.46) | IDO1MAPTTDP1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221392-B2 | Generation of pancreatic endoderm from pluripotent stem cells using small molecules | NOVO NORDISK A/S (DK) | 2019-03-05 | — | — | US | disclosed |
| EP-1158320-B1 | Dichroic light polarizers | NITTO DENKO CORP (JP) | 2008-08-06 | — | — | EP | disclosed |