SCHEMBL2588752

SCHEMBL2588752

C=CC[SiH](CCCCC)O[SiH3]

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480239 0.80 TSHR (0.37) TSHR
SCHEMBL5615425 0.78 TSHR (0.42) TSHRALDH1A1
SCHEMBL5615452 0.78 TSHR (0.42) TSHRALDH1A1
SCHEMBL8651054 0.78 TSHR (0.42) TSHRALDH1A1
SCHEMBL5615295 0.78 TSHR (0.42) TSHRALDH1A1
SCHEMBL5615189 0.78 TSHR (0.42) TSHRALDH1A1
SCHEMBL5615509 0.78 TSHR (0.42) TSHRALDH1A1
SCHEMBL5615496 0.78 TSHR (0.42) TSHRALDH1A1
SCHEMBL18763581 0.76
SCHEMBL44553 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113071030-B Hole sealing release agent and preparation method thereof 东莞市凯文化工有限公司 2023-03-17 CN claimed
WO-2023009315-A1 A SUNSCREEN COMPOSITION COMPRISING AVOBENZONE AND A METHOD FOR PHOTOSTABILIZATION ISP INVESTMENTS LLC (US) 2023-02-02 WO claimed
CN-113071030-A Hole sealing release agent and preparation method thereof 东莞市凯文化工有限公司 2021-07-06 CN claimed
CN-101641615-B Silicone-containing prepolymers with dangling hydrophilic polymer chains NOVARTIS AG 2012-06-06 CN claimed
CN-101641615-A Silicone-containing prepolymers with dangling hydrophilic polymer chains NOVARTIS AG CH 2010-02-03 CN claimed
JP-4246383-B2 2009-04-02 JP claimed
US-20050101704-A1 Flame retardant additive for polymers compounds with improved hydro-thermal stability CLARIANT GMBH 2005-05-12 US claimed
CN-1199057-C Photocurable siloxane polymers PHARMACIA & UPJOHN CRONINJGEN (NL) 2005-04-27 CN claimed
US-6613815-B2 Water, a colorant, and ethylene oxide-propylene oxide-spacer-siloxane block copolymer; dry time is decreased to reduce bleeding between colors XEROX CORPORATION 2003-09-02 US claimed
US-6528557-B2 Ink containing a polyoxyalkylene glycol-polysiloxane block copolymer having optional spacer groups of given formula; multicolor ink jet printing with reduced dry time and/or intercolor bleed XEROX CORPORATION 2003-03-04 US claimed
JP-2001521967-A 2001-11-13 JP claimed
EP-1084189-A1 EXTRUDABLE VINYLIDENE CHLORIDE POLYMER COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 2001-03-21 EP claimed
EP-1025164-A1 EXTRUDABLE VINYLIDENE CHLORIDE POLYMER COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 2000-08-09 EP claimed
WO-1999058603-A1 EXTRUDABLE VINYLIDENE CHLORIDE POLYMER COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1999-11-18 WO claimed
US-5986003-A BLEND WITH SILICONE POLYMER AND POLYOLEFIN CARRIER THE DOW CHEMICAL COMPANY (US) 1999-11-16 US claimed
US-5912291-A WETTING SOME OF THE RESIN PARTICLES WITH THE POLYSILOXANE ADDITIVE BEFORE HIGH SHEAR MIXING YIELDS BLEND HAVING HIGHER CONCENTRATIONS OF ADDITIVE AT SURFACES AFTER COOLING AND SOLIDIFICATION, PHYSICAL PROPERTIES RES DEVELOPMENT CORPORATION (US) 1999-06-15 US claimed
WO-1999023158-A1 EXTRUDABLE VINYLIDENE CHLORIDE POLYMER COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1999-05-14 WO claimed
EP-0476115-A1 PROCESS TO SEPARATE DIOXYGEN FROM A GAS MIXTURE L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1992-03-25 EP claimed
WO-1991014649-A1 PROCESS TO SEPARATE DIOXYGEN FROM A GAS MIXTURE L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1991-10-03 WO claimed
US-4339339-A Hydrostatically damping and shock absorbing non-vulcanizable polysiloxane and boron compound for mechanical energy absorption INSTYTUT CHEMII PRZEMYSLOWEJ (PL) 1982-07-13 US claimed