Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27866562 | 0.86 | MAPT (0.35) | MAPTALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL6156721 | 0.79 | ALDH1A1 (0.39) | MAPTALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL6156717 | 0.79 | ALDH1A1 (0.39) | MAPTALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL6156709 | 0.79 | ALDH1A1 (0.39) | MAPTALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL2770831 | 0.78 | MAPT (0.33) | MAPTALDH1A1GLO1LMNAHSD17B10 | |
| SCHEMBL2770827 | 0.78 | MAPT (0.33) | MAPTALDH1A1GLO1LMNAHSD17B10 | |
| SCHEMBL8488566 | 0.75 | MAPT (0.34) | MAPTNPSR1GLO1MMP8CYP2D6 | |
| SCHEMBL951120 | 0.74 | MAPT (0.36) | MAPTALDH1A1NPSR1GLO1TSHR | |
| SCHEMBL951119 | 0.74 | MAPT (0.36) | MAPTALDH1A1NPSR1GLO1TSHR | |
| SCHEMBL4836138 | 0.74 | ALDH1A1 (0.42) | MAPTALDH1A1NPSR1GLO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |