Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25890612 | 1.00 | MAPK1 (0.40) | MAPK1KCNN4ALDH1A1ALOX15CA4 | |
| SCHEMBL89308 | 0.77 | KCNN4 (0.44) | MAPK1KCNN4ALDH1A1ALOX15TAAR1 | |
| SCHEMBL15434945 | 0.77 | KCNN4 (0.44) | MAPK1KCNN4ALDH1A1ALOX15TAAR1 | |
| SCHEMBL19185256 | 0.75 | KCNN4 (0.38) | MAPK1KCNN4ALDH1A1ALOX15TAAR1 | |
| SCHEMBL9279074 | 0.71 | MAPK1 (0.46) | MAPK1KCNN4ALDH1A1ALOX15TAAR1 | |
| SCHEMBL575235 | 0.71 | MAPK1 (0.46) | MAPK1KCNN4ALDH1A1ALOX15TAAR1 | |
| SCHEMBL11480693 | 0.70 | MAPK1 (0.46) | MAPK1KCNN4ALDH1A1ALOX15TAAR1 | |
| SCHEMBL25432602 | 0.69 | KMT2A (0.48) | KCNN4ALDH1A1ALOX15HDAC3HDAC4 | |
| SCHEMBL4352236 | 0.69 | MAPK1 (0.44) | MAPK1KCNN4ALDH1A1ALOX15TAAR1 | |
| SCHEMBL2429063 | 0.69 | ALDH1A1 (0.46) | MAPK1ALDH1A1ALOX15TAAR1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |