Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434945 | 1.00 | KCNN4 (0.44) | KCNN4MAPK1TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL19185256 | 0.80 | KCNN4 (0.38) | KCNN4MAPK1TAAR1ALOX15CYP3A4 | |
| SCHEMBL14233970 | 0.78 | KCNN4 (0.41) | KCNN4MAPK1TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL14154663 | 0.78 | KCNN4 (0.41) | KCNN4MAPK1TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL14693066 | 0.78 | ALOX15 (0.44) | KCNN4MAPK1TAAR1SLC18A2SIGMAR1 | |
| SCHEMBL24115139 | 0.78 | ESR1 (0.48) | CYP3A4TSHRHSD17B10ALDH1A1MEN1 | |
| SCHEMBL25890612 | 0.77 | MAPK1 (0.40) | KCNN4MAPK1TAAR1ALOX15CYP3A4 | |
| SCHEMBL25890609 | 0.77 | MAPK1 (0.40) | KCNN4MAPK1TAAR1ALOX15CYP3A4 | |
| SCHEMBL23394104 | 0.77 | PRMT6 (0.42) | TAAR1SLC18A2SIGMAR1CYP3A4ADRA1A | |
| SCHEMBL11192903 | 0.76 | CYP2D6 (0.48) | KCNN4MAPK1TAAR1SLC18A2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943499-A2 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE | Samsung Electronics Co., Ltd. (KR) | 2022-01-26 | — | — | EP | disclosed |
| EP-2374454-A1 | Hemiasterlin derivatives and uses thereof in the treatment of cancer | Eisai R&D Management Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |