Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 4/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25890713 | 0.81 | SLC6A2 (0.50) | MEN1LMNAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL25890717 | 0.80 | MEN1 (0.51) | MEN1LMNAKMT2ASLC6A3 | |
| SCHEMBL25890759 | 0.77 | SLC6A3 (0.37) | MEN1KMT2ASMN1; SMN2SLC6A3 | |
| SCHEMBL10006263 | 0.75 | SLC6A3 (0.59) | SLC6A3 | |
| SCHEMBL19650801 | 0.75 | TRPV1 (0.43) | TRPV1PDE2AMEN1LMNAHTT | |
| SCHEMBL434632 | 0.74 | PDE2A (0.46) | TRPV1PDE2A | |
| SCHEMBL25890774 | 0.73 | SLC6A3 (0.47) | MEN1KMT2ASLC6A3 | |
| SCHEMBL19650798 | 0.73 | TRPV1 (0.43) | TRPV1PDE2A | |
| SCHEMBL26081058 | 0.71 | DHODH (0.50) | TRPV1PDE2AMEN1LMNAHTT | |
| SCHEMBL454274 | 0.69 | HTR2C (0.49) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |