Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25890713 | 0.81 | SLC6A2 (0.50) | SLC6A3SLC6A2SLC6A4ALDH1A1MEN1 | |
| SCHEMBL25890717 | 0.80 | MEN1 (0.51) | SLC6A3SLC6A2ALDH1A1MEN1MAPK1 | |
| SCHEMBL25890745 | 0.77 | TRPV1 (0.42) | SLC6A3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25890774 | 0.73 | SLC6A3 (0.47) | SLC6A3SLC6A2SLC6A4ALDH1A1MEN1 | |
| SCHEMBL11264797 | 0.71 | GAA (0.60) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL16757423 | 0.70 | ALDH1A1 (0.38) | SLC6A3SLC6A2SLC6A4ALDH1A1MEN1 | |
| SCHEMBL12159411 | 0.69 | SMN1; SMN2 (0.37) | SLC6A3SLC6A2SLC6A4ALDH1A1MEN1 | |
| SCHEMBL18120335 | 0.67 | ALDH1A1 (0.35) | SLC6A3SLC6A2SLC6A4ALDH1A1MEN1 | |
| SCHEMBL25890721 | 0.67 | LMNA (0.43) | ALDH1A1MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL2063751 | 0.65 | SMN1; SMN2 (0.39) | SLC6A3SLC6A2SLC6A4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3877372-B1 | ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS | SYNGENTA CROP PROTECTION AG (CH) | 2023-08-02 | — | — | EP | disclosed |