Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24499183 | 0.95 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL6407607 | 0.88 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL9313874 | 0.86 | L3MBTL1 (0.76) | L3MBTL1ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL15267699 | 0.84 | KMT2A (0.60) | ALDH1A1HTTRAB9ANPC1MAPT | |
| SCHEMBL31703797 | 0.83 | MTNR1B (0.78) | HPGDTP53 | |
| SCHEMBL2954416 | 0.83 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL2089592 | 0.83 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL2089593 | 0.83 | L3MBTL1 (0.71) | L3MBTL1ALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL6424909 | 0.82 | POLB (0.77) | ALDH1A1HTTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1117828 | 0.81 | L3MBTL1 (0.69) | L3MBTL1ALDH1A1HTTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459362-A | N-aryl-2- (2-hydroxybenzyloxy) acetamides, preparation method and application thereof | 湖南科技大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-118255686-A | Fluorine-containing trans-phenyl cyclopropylamine derivative, and preparation method and application thereof | 郑州大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-117304033-A | Caffeic acid derivative and preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2023-12-29 | — | — | CN | disclosed |
| CN-117003744-A | Five-membered and six-membered compound, intermediate, preparation method, composition and application | 厦门市博瑞来医药科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-110790724-B | Selective carbonic anhydrase inhibitor and synthesis method and application thereof | 中山大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-110790724-A | Selective carbonic anhydrase inhibitor and synthesis method and application thereof | 中山大学 | 2020-02-14 | — | — | CN | disclosed |
| EP-2758370-A1 | PARP INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013030205-A1 | PARP INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-03-07 | — | — | WO | disclosed |
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |
| US-6991902-B2 | Nucleobase heterocyclic combinatorialization | ISIS PHARMACEUTICALS, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-5780241-A | ALTERING ELECTROCHEMICAL PROPERTIES BY DECYCLIZATION | ISIS PHARMACEUTICALS, INC. (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1998020349-A1 | COMPLEX CHEMICAL LIBRARIES | ISIS PHARMACEUTICALS, INC. (US) | 1998-05-14 | — | — | WO | disclosed |
| EP-0838465-A1 | Pyridinium-substituted (lactamylvinyl)cephalosporin derivatives, their preparation and their use as antibiotics | F. HOFFMANN-LA ROCHE AG (CH) | 1998-04-29 | — | — | EP | disclosed |
| US-5731438-A | BACTERICIDES; DRUGS | ISIS PHARMACEUTICALS, INC. (US) | 1998-03-24 | — | — | US | disclosed |
| WO-1998006671-A1 | METHODS FOR REMOVING UNREACTED ELECTROPHILES FROM A REACTION MIXTURE | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-19 | — | — | WO | disclosed |
| WO-1998005332-A1 | NOVEL HETEROCYCLE COMPOSITIONS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-12 | — | — | WO | disclosed |
| US-5632898-A | SCAVINGING WITH A WATER-SOLUBLE NUCLEOPHILE COMPRISING AMINO-, HYDROXY- OR MERCAPTO-CONTAINING SULFONATES, CARBOXYLATES OR PHOSPHONATES FOLLOWED BY SEPARATION | ISIS PHARMACEUTICALS, INC. (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0034292-B1 | PROCESS FOR THE PREPARATION OF ANTHRANILIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-11-23 | — | — | EP | disclosed |
| EP-0034292-A2 | Process for the preparation of anthranilic acid derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-08-26 | — | — | EP | disclosed |
| US-4102924-A | REACTING ACYLAMINO-ARYLS WITH HALO-ARYLS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-25 | — | — | US | disclosed |