SCHEMBL25891228

SCHEMBL25891228

CC(C)C(NC(=O)CNC(=O)CNC(=O)CN1CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC1)C(=O)N[C@H](C)C(=O)N1CCC[C@H]1B(O)O

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 11/20 0.49
▸ PREP P48147 10/20 0.49
▸ DPP4 P27487 13/20 0.47
▸ DPP8 Q6V1X1 8/20 0.47
▸ DPP9 Q86TI2 7/20 0.47
▸ DPP7 Q9UHL4 9/20 0.41
▸ PITRM1 Q5JRX3 1/20 0.41
▸ ELANE P08246 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27260568 1.00 FAP (0.49) FAPPREPDPP4DPP8DPP9
SCHEMBL25891871 1.00 FAP (0.49) FAPPREPDPP4DPP8DPP9
SCHEMBL25894962 1.00 FAP (0.49) FAPPREPDPP4DPP8DPP9
SCHEMBL27261585 1.00 FAP (0.49) FAPPREPDPP4DPP8DPP9
SCHEMBL25895023 1.00 FAP (0.49) FAPPREPDPP4DPP8DPP9
SCHEMBL25894986 1.00 FAP (0.49) FAPPREPDPP4DPP8DPP9
SCHEMBL25892262 0.99 FAP (0.50) FAPPREPDPP4DPP8DPP9
SCHEMBL25891862 0.99 FAP (0.50) FAPPREPDPP4DPP8DPP9
SCHEMBL27261389 0.96 FAP (0.47) FAPPREPDPP4DPP8DPP9
SCHEMBL25895232 0.93 FAP (0.47) FAPPREPDPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230330275-A1 FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO TRUSTEES OF TUFTS COLLEGE 2023-10-19 — — US disclosed
US-11707539-B2 FAP-targeted radiopharmaceuticals and imaging agents, and uses related thereto TRUSTEES OF TUFTS COLLEGE (US) 2023-07-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330275-A1 FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO FAP, APC, FIBP FAP 1/4885PREP 543/4885DPP4 147/4885
US-11707539-B2 FAP-targeted radiopharmaceuticals and imaging agents, and uses related thereto FAP, APC, FIBP FAP 1/4885PREP 543/4885DPP4 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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