Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 15/20 | 0.49 |
| ▸ | FAP | Q12884 | 13/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25892788 | 0.97 | PREP (0.46) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL25892815 | 0.97 | PREP (0.47) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL27257349 | 0.97 | PREP (0.46) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL25892832 | 0.95 | PREP (0.45) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL26574665 | 0.94 | PREP (0.45) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL25892757 | 0.93 | PREP (0.47) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL27263007 | 0.93 | PREP (0.47) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL27262840 | 0.92 | PREP (0.47) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL25896601 | 0.91 | PREP (0.49) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL23876514 | 0.91 | PREP (0.51) | PREPFAPDPP8DPP9DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11707539-B2 | FAP-targeted radiopharmaceuticals and imaging agents, and uses related thereto | TRUSTEES OF TUFTS COLLEGE (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11707539-B2 | FAP-targeted radiopharmaceuticals and imaging agents, and uses related thereto | FAP, APC, FIBP | PREP 543/4885FAP 1/4885DPP8 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.