SCHEMBL25893403

SCHEMBL25893403

Clc1cccc2sc3c(-c4ccc(Br)cc4)cccc3c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
MAPK1 P28482 1/20 0.36
MCL1 Q07820 1/20 0.36
LIMK1 P53667 2/20 0.33
PLK4 O00444 1/20 0.33
AURKA O14965 1/20 0.33
JAK2 O60674 1/20 0.33
LCK P06239 1/20 0.33
CDK1 P06493 1/20 0.33
CSF1R P07333 1/20 0.33
LYN P07948 1/20 0.33
FGFR1 P11362 1/20 0.33
SRC P12931 1/20 0.33
PRKACA P17612 1/20 0.33
RPS6KB1 P23443 1/20 0.33
CDK2 P24941 1/20 0.33
MARK3 P27448 1/20 0.33
AKT1 P31749 1/20 0.33
AKT2 P31751 1/20 0.33
KDR P35968 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23765008 0.87 PLK4 (0.35) ALOX5MAPK1MCL1LIMK1PLK4
SCHEMBL25567635 0.86 ALOX5 (0.46) ALOX5MAPK1MCL1LIMK1MAPT
SCHEMBL22019102 0.86 CYP2A6 (0.47) ALOX5MAPK1MCL1LIMK1MAPT
SCHEMBL22892795 0.83 ALOX5 (0.38) ALOX5MAPK1LIMK1PLK4AURKA
SCHEMBL2597559 0.81 ALOX5 (0.60) ALOX5MAPK1LIMK1MAPTPARP14
SCHEMBL21398775 0.80 ALOX5 (0.41) ALOX5MAPK1MCL1LIMK1MAPT
SCHEMBL29489079 0.80 ALOX5 (0.59) ALOX5MAPK1LIMK1MAPTPARP14
SCHEMBL10044990 0.80 ALOX5 (0.59) ALOX5MAPK1LIMK1MAPTPARP14
SCHEMBL21428316 0.78 ALOX5 (0.57) ALOX5MAPK1LIMK1MAPTPARP14
SCHEMBL23765150 0.78 PTPN1 (0.40) ALOX5MAPK1MCL1OGG1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023140528-A1 ORGANIC ELECTRIC ELEMENT USING COMPOUND FOR ORGANIC ELECTRIC ELEMENT, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2023-07-27 WO disclosed