Known targets — ChEMBL curated mechanism
823298382338688239847Rdl1Rdl2Rdl3
The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | GABRA1 | P14867 | 1/20 | 1.00 |
| ▸ | GABRB1 | P18505 | 1/20 | 1.00 |
| ▸ | GABRG2 | P18507 | 1/20 | 1.00 |
| ▸ | GABRR1 | P24046 | 1/20 | 1.00 |
| ▸ | GABRB3 | P28472 | 1/20 | 1.00 |
| ▸ | GABRA6 | Q16445 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lindane SCHEMBL8575655 | 1.00 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL10795898 | 1.00 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL9120917 | 1.00 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Alpha-Hexachlorocyclohexane SCHEMBL140813 | 1.00 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL75689 | 1.00 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL472088 | 1.00 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| SCHEMBL8406626 | 1.00 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL8110265 | 1.00 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL9242537 | 1.00 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 | |
| Lindane SCHEMBL140812 | 1.00 | LMNA (1.00) | LMNACYP3A4GABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 92047 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137082-A1 | FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL | SYNGENTA CROP PROTECTION AG (CH) | 2026-05-21 | — | — | US | claimed |
| US-12622925-B2 | Edible enterosorbents used to mitigate acute exposures to ingestible environmental toxins following outbreaks, natural disasters and emergencies | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2026-05-12 | — | — | US | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4719059-A1 | INCREASED PALATABILITY OF INSECTICIDAL INSECT BAITS | Bio Logic Crop Science, S.L. (ES) | 2026-04-08 | — | — | EP | claimed |
| US-20260092926-A1 | BIOLOGICAL STATUS CLASSIFICATION | RANDOX LABORATORIES LTD (GB) | 2026-04-02 | — | — | US | claimed |
| WO-2025244856-A1 | METHODS AND COMPOSITIONS RELATING TO ELQ COMPOUNDS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2025-11-27 | — | — | WO | claimed |
| US-12471599-B2 | Agricultural compositions comprising remodeled nitrogen fixing microbes | PIVOT BIO, INC. (US) | 2025-11-18 | — | — | US | claimed |
| US-20250346506-A1 | Membrane-Mediated Electro-Oxidation-Reduction Deep Water Treatment Device and its Operation Method Thereof | HARBIN INST TECHNOLOGY (CN) | 2025-11-13 | — | — | US | claimed |
| EP-3578542-B1 | COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO | CORTEVA AGRISCIENCE LLC (US) | 2025-11-12 | — | — | EP | claimed |
| EP-4646109-A2 | NATURAL LIPID PARTICLE FORMULATIONS FOR AGRICULTURAL APPLICATIONS | Invaio Sciences, Inc. (US) | 2025-11-12 | — | — | EP | claimed |
| US-4146180-A | Retractable environmental seal | NASA | 1979-03-27 | — | — | US | claimed |
| US-4119323-A | Heat and solvent resistant flexible gasket means and process for production thereof | HERBERT MEISTER AND CO. (CH) | 1978-10-10 | — | — | US | claimed |
| US-4103450-A | LOW DENSITY WEB IMPREGNATED WITH INSECTICIDE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-08-01 | — | — | US | claimed |
| US-4065159-A | Rotary connector | Sprunck, E. (FR) | 1977-12-27 | — | — | US | claimed |
| US-4052221-A | CHLORINATED NAPTHALENE, PARATERPHENYL, SEMICONDUCTOR WAFER | WESTERN ELECTRIC COMPANY, INC. (US) | 1977-10-04 | — | — | US | claimed |
| US-4034080-A | 4-METHYL-3-HEPTANOL, 2,4-DIMETHYL-5-ETHYL-6,8-DIOXA-BICYCLO(3.2.1)OCTANE, ALPHA-CUBEBENE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-07-05 | — | — | US | claimed |
| US-3982559-A | High temperature fluid pressure control valve | OCHS PAUL | 1976-09-28 | — | — | US | claimed |
| US-3977600-A | Temperature responsive fluid flow regulator | J. I. CASE COMPANY (US) | 1976-08-31 | — | — | US | claimed |
| US-3970494-A | Method for adhering one surface to another | WESTERN ELECTRIC CO., INC. (US) | 1976-07-20 | — | — | US | claimed |
| US-3945650-A | Lip seal assembly | INNOVATEX CORPORATION (US) | 1976-03-23 | — | — | US | claimed |