SCHEMBL25895202

SCHEMBL25895202

Clc1nc(-c2ccccc2)nc(-c2ccc3cc(C4C=CC=CC4)ccc3c2)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 1/20 0.35
CYP1A2 P05177 1/20 0.35
HSD17B10 Q99714 1/20 0.35
EGFR P00533 8/20 0.34
ERBB2 P04626 8/20 0.34
ERBB3 P21860 2/20 0.33
KDR P35968 2/20 0.33
PTK2 Q05397 2/20 0.33
HPGD P15428 3/20 0.32
MAPT P10636 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
LMNA P02545 1/20 0.31
ACHE P22303 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24727361 0.90 MEN1 (0.35) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL20648201 0.89 MEN1 (0.34) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL24054463 0.84 MEN1 (0.33) MEN1KMT2AALDH1A1SMN1; SMN2HPGD
SCHEMBL18866852 0.82 L3MBTL1 (0.38) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL25894677 0.81 NR1H4 (0.33) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL25118679 0.79 MEN1 (0.36) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL18931358 0.79 MEN1 (0.34) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL15128338 0.78 MEN1 (0.36) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL25706397 0.78 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2HPGDMAPT
SCHEMBL27371535 0.78 KDM4E (0.32) MEN1KMT2AALDH1A1KDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132694-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-07-13 WO disclosed