SCHEMBL25895634

SCHEMBL25895634

C[C@@H](NC(=O)c1ccc(NNC(=O)CN2CCN(CC(=O)O)CCN(CC(=O)O)CCN(CC(=O)O)CC2)nc1)C(=O)N1CCC[C@H]1B(O)O

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PREP P48147 17/20 0.56
▸ FAP Q12884 16/20 0.56
▸ DPP8 Q6V1X1 4/20 0.54
▸ DPP9 Q86TI2 4/20 0.54
▸ DPP4 P27487 3/20 0.37
▸ ELANE P08246 1/20 0.37
▸ DPP7 Q9UHL4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25893738 0.92 PREP (0.49) PREPFAPDPP8DPP9DPP4
SCHEMBL26576870 0.91 PREP (0.48) PREPFAPDPP8DPP9DPP4
SCHEMBL26576636 0.90 PREP (0.49) PREPFAPDPP8DPP9DPP4
SCHEMBL25896315 0.88 FAP (0.61) PREPFAPDPP8DPP9DPP4
SCHEMBL27257134 0.88 PREP (0.50) PREPFAPDPP8DPP9DPP4
SCHEMBL23876869 0.88 PREP (0.63) PREPFAPDPP8DPP9DPP4
SCHEMBL25891558 0.88 PREP (0.63) PREPFAPDPP8DPP9DPP4
SCHEMBL25891171 0.86 PREP (0.61) PREPFAPDPP8DPP9DPP4
SCHEMBL25892342 0.85 PREP (0.56) PREPFAPDPP8DPP9DPP4
SCHEMBL25890456 0.85 PREP (0.60) PREPFAPDPP8DPP9DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207292-A1 BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS TRUSTEES OF TUFTS COLLEGE 2024-06-27 — — US disclosed
US-20230330275-A1 FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO TRUSTEES OF TUFTS COLLEGE 2023-10-19 — — US disclosed
US-11707539-B2 FAP-targeted radiopharmaceuticals and imaging agents, and uses related thereto TRUSTEES OF TUFTS COLLEGE (US) 2023-07-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330275-A1 FAP-TARGETED RADIOPHARMACEUTICALS AND IMAGING AGENTS, AND USES RELATED THERETO FAP, APC, FIBP PREP 543/4885FAP 1/4885DPP8 223/4885
US-11707539-B2 FAP-targeted radiopharmaceuticals and imaging agents, and uses related thereto FAP, APC, FIBP PREP 543/4885FAP 1/4885DPP8 223/4885
US-20240207292-A1 BORONIC ACID COMPOUNDS, COMPOSITIONS AND METHODS BCL6B, BCL6, BTD PREP 2680/4885FAP 1959/4885DPP8 3921/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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