Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25919939 | 0.99 | PAOX (0.37) | PAOXALDH1A1 | |
| SCHEMBL25919936 | 0.99 | PAOX (0.37) | PAOXALDH1A1 | |
| SCHEMBL10330544 | 0.81 | — | — | |
| SCHEMBL26616375 | 0.76 | PAOX (0.32) | PAOX | |
| SCHEMBL20026584 | 0.75 | EPHX1 (0.40) | PAOXALDH1A1 | |
| SCHEMBL26972905 | 0.75 | PAOX (0.31) | PAOX | |
| SCHEMBL20026472 | 0.74 | EPHX1 (0.42) | PAOXALDH1A1 | |
| SCHEMBL25825777 | 0.74 | EPHX1 (0.42) | PAOXALDH1A1 | |
| SCHEMBL22353370 | 0.74 | PRMT3 (0.37) | — | |
| SCHEMBL25920340 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218795-A2 | PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS | Ascendis Pharma Bone Diseases A/S (DK) | 2023-08-02 | — | — | EP | disclosed |
| US-20230218722-A1 | PTH Compounds with Low Peak-To-Trough Ratios | ASCENDIS PHARMA BONE DISEASES AS (DK) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218722-A1 | PTH Compounds with Low Peak-To-Trough Ratios | PTH1R, PTMS, FGF23 | PAOX 3905/4885ALDH1A1 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.