Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20029362 | 0.82 | — | — | |
| SCHEMBL22353370 | 0.81 | PRMT3 (0.37) | — | |
| SCHEMBL20614476 | 0.74 | KDM4C (0.31) | KDM4C | |
| SCHEMBL729759 | 0.72 | — | — | |
| SCHEMBL968065 | 0.71 | CA12 (0.32) | HDAC3HDAC1HDAC2CA12CA2 | |
| SCHEMBL969640 | 0.70 | ALDH1A1 (0.39) | HDAC3HDAC1HDAC2KDM4CCA12 | |
| Ammonia Solution, Strong SCHEMBL27978398 | 0.70 | CA12 (0.40) | HDAC3HDAC1HDAC2KDM4CCA12 | |
| Fluoride SCHEMBL28555435 | 0.70 | CA12 (0.36) | HDAC3HDAC1HDAC2KDM4CCA12 | |
| SCHEMBL9972415 | 0.69 | KDM4C (0.44) | KDM4C | |
| SCHEMBL21250586 | 0.68 | ALDH1A1 (0.36) | CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4218795-A2 | PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS | Ascendis Pharma Bone Diseases A/S (DK) | 2023-08-02 | — | — | EP | disclosed |