Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13252969 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL9129040 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL26700310 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL19819225 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL14748100 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2A | |
| SCHEMBL24023602 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL2616323 | 0.75 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL763146 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL19601657 | 0.74 | RORC (0.44) | ALDH1A1MEN1KMT2AGAAHPGD | |
| SCHEMBL15445211 | 0.74 | XIAP (0.42) | ALDH1A1HPGDRORCHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713322-B2 | Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer | CAPELLA THERAPEUTICS, INC. (US) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713322-B2 | Benzimidazole derivatives as ERBB tyrosine kinase inhibitors for the treatment of cancer | ERBB2, ERBB4, ERBB3 | ALDH1A1 1322/4885MEN1 3758/4885KMT2A 2060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.