SCHEMBL258974

SCHEMBL258974

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nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
SLC13A5 Q86YT5 8/20 0.46
HMGCR P04035 1/20 0.40
CHRM1 P11229 1/20 0.40
TBXA2R P21731 1/20 0.40
ADRA1A P35348 1/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
THRB P10828 1/20 0.40
KMT2A Q03164 1/20 0.40
NAALAD2 Q9Y3Q0 1/20 0.39
TSHR P16473 2/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
ACLY P53396 3/20 0.38
LMNA P02545 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111251 1.00 ALDH1A1 (0.67) ALDH1A1SLC13A5HMGCRCHRM1TBXA2R
SCHEMBL13780139 1.00 ALDH1A1 (0.67) ALDH1A1SLC13A5HMGCRCHRM1TBXA2R
Alpha-Ketoglutaric Acid SCHEMBL6064725 0.88 EGLN1 (0.54) ALDH1A1SLC13A5HMGCRCHRM1TBXA2R
Alpha-Ketoglutaric Acid SCHEMBL1498891 0.88 EGLN1 (0.54) ALDH1A1SLC13A5HMGCRCHRM1TBXA2R
SCHEMBL3105548 0.87 ALDH1A1 (0.52) ALDH1A1HMGCRCHRM1TBXA2RADRA1A
SCHEMBL31738893 0.86 ALDH1A1 (0.61) ALDH1A1SLC13A5HMGCRCHRM1TBXA2R
SCHEMBL10052698 0.86 ALDH1A1 (0.61) ALDH1A1SLC13A5HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL9795594 0.84 ALDH1A1 (0.83) ALDH1A1SLC13A5HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL119740 0.84 ALDH1A1 (0.83) ALDH1A1SLC13A5HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL1871341 0.84 ALDH1A1 (0.83) ALDH1A1SLC13A5HMGCRCHRM1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026102230-A2 INCREASED NITROGEN FIXATION USING BACTERIA WITH MODIFIED ELECTRON TRANSPORT GENES Bayer CropScience LLC (US) 2026-05-15 WO disclosed
US-12416012-B2 Expression of nitrogenase polypeptides in plant cells COMMONWEALTH SCIENTIFIC INDUSTRIAL RESEARCH ORGANISATION 2025-09-16 US disclosed
WO-2025043298-A1 NIF VARIANTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2025-03-06 WO disclosed
US-20240117326-A1 EXPRESSION OF NITROGENASE POLYPEPTIDES IN PLANT CELLS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2024-04-11 US disclosed
US-11441166-B2 Redox enzyme-embedded pyrene-poly(ethylenimine) hydrogel electrode for electrosynthesis UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2022-09-13 US disclosed
EP-4041892-A1 EXPRESSION OF NITROGENASE POLYPEPTIDES IN PLANT CELLS Commonwealth Scientific and Industrial Research Organisation (AU) 2022-08-17 EP disclosed
US-20220170038-A1 Expression of Nitrogenase Polypeptides In Plant Cells COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2022-06-02 US disclosed
EP-3935169-A1 EXPRESSION OF NITROGENASE POLYPEPTIDES IN PLANT CELLS Commonwealth Scientific and Industrial Research Organisation (AU) 2022-01-12 EP disclosed
WO-2021068039-A1 EXPRESSION OF NITROGENASE POLYPEPTIDES IN PLANT CELLS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2021-04-15 WO disclosed
WO-2020181324-A1 EXPRESSION OF NITROGENASE POLYPEPTIDES IN PLANT CELLS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2020-09-17 WO disclosed
EP-2366026-A2 BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES FROM ALPHA KETOACIDS Celexion, Llc (US) 2011-09-21 EP disclosed
US-20110171696-A1 Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks CELEXION, LLC (US) 2011-07-14 US disclosed
US-20110171696-A1 Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks CELEXION, LLC (US) 2011-07-14 US disclosed
US-20110171696-A1 Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks CELEXION, LLC (US) 2011-07-14 US disclosed
US-20100151536-A1 Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks CELEXION, LLC 2010-06-17 US disclosed
US-20100151536-A1 Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks CELEXION, LLC 2010-06-17 US disclosed
US-20100151536-A1 Biological Synthesis of Difunctional Alkanes from Carbohydrate Feedstocks CELEXION, LLC 2010-06-17 US disclosed
WO-2010068944-A2 BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES FROM CARBOHYDRATE FEEDSTOCKS CELEXION, LLC (US) 2010-06-17 WO disclosed
US-20090187041-A1 ESTERS OF (2-HYDROXY-3-OXO-CYCLOPENT-1-ENYL) ACETIC ACID AND THEIR USE FOR PREPARING (-)-R-HOMOCITRIC ACID GAMMA-LACTONE, (+)-S-HOMOCITRIC ACID GAMMA-LACTONE AND THE CORRESPONDING (-)-R-HOMOCITRIC ACID AND (+)-S-HOMOCITRIC ACID SALTS TALLINN UNIVERSITY OF TECHNOLOGY (EE) 2009-07-23 US disclosed
WO-2007137593-A1 ESTERS OF (2-HYDROXY-3-OXO-CYCLOPENT-1-ENYL) ACETIC ACID AND THEIR USE FOR PREPARING (-)-R-HOMOCITRIC ACID GAMMA-LACTONE, (+)-S-HOMOCITRIC ACID GAMMA-LACTONE AND THE CORRESPONDING (-)-R-HOMOCITRIC ACID AND (+)-S-HOMOCITRIC ACID SALTS TALLINN UNIVERSITY OF TECHNOLOGY (EE) 2007-12-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090187041-A1 ESTERS OF (2-HYDROXY-3-OXO-CYCLOPENT-1-ENYL) ACETIC ACID AND THEIR USE FOR PREPARING (-)-R-HOMOCITRIC ACID GAMMA-LACTONE, (+)-S-HOMOCITRIC ACID GAMMA-LACTONE AND THE CORRESPONDING (-)-R-HOMOCITRIC ACID AND (+)-S-HOMOCITRIC ACID SALTS HACL2, CYP8B1, HCAR1 ALDH1A1 359/4885SLC13A5 2835/4885HMGCR 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.