Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 12/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31058433 | 0.97 | LMNA (0.40) | LMNAHTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL25898801 | 0.89 | GRM2 (0.40) | LMNAHTTKDM4EMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31058409 | 0.89 | SIK2 (0.38) | LMNAHTTKDM4EMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL26658801 | 0.89 | SIK2 (0.38) | LMNAHTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL25898806 | 0.88 | LMNA (0.40) | LMNAHTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL25320350 | 0.87 | TIPARP (0.35) | LMNAHTTGRM2TSHRTIPARP | |
| SCHEMBL30550698 | 0.87 | TIPARP (0.35) | LMNAHTTGRM2TSHRTIPARP | |
| SCHEMBL25898794 | 0.86 | TIPARP (0.42) | LMNAHTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL25899251 | 0.85 | TIPARP (0.46) | LMNAHTTKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL25321271 | 0.85 | TIPARP (0.33) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |