Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 4/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25320350 | 1.00 | TIPARP (0.35) | TIPARPGRM2LMNATSHRHTT | |
| SCHEMBL31058433 | 0.90 | LMNA (0.40) | TIPARPGRM2LMNATSHRHTT | |
| SCHEMBL25898093 | 0.87 | LMNA (0.41) | TIPARPGRM2LMNATSHRHTT | |
| Hydrochloric Acid SCHEMBL31058409 | 0.86 | SIK2 (0.38) | TIPARPGRM2LMNAHTT | |
| Hydrochloric Acid SCHEMBL26658801 | 0.86 | SIK2 (0.38) | TIPARPGRM2LMNAHTT | |
| SCHEMBL30550707 | 0.83 | GRM2 (0.31) | TIPARPGRM2 | |
| SCHEMBL25322088 | 0.83 | GRM2 (0.31) | TIPARPGRM2 | |
| SCHEMBL25321271 | 0.82 | TIPARP (0.33) | TIPARP | |
| SCHEMBL25321451 | 0.82 | TIPARP (0.37) | TIPARP | |
| SCHEMBL25321448 | 0.82 | TIPARP (0.37) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469448-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118591537-A | PARP7 inhibitors | 吉利德科学公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |