Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 12/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25899139 | 0.90 | AR (0.75) | ARHDAC8HDAC6PGRCYP2C9 | |
| SCHEMBL24031262 | 0.90 | AR (0.70) | ARHDAC8HDAC6PGRCYP2C9 | |
| SCHEMBL24031261 | 0.90 | AR (0.63) | ARHDAC8HDAC6PGRS1PR3 | |
| SCHEMBL26804334 | 0.87 | AR (0.73) | ARHDAC8HDAC6PGRSMYD3 | |
| SCHEMBL24031591 | 0.87 | AR (0.66) | ARHDAC8HDAC6PGRCYP2C9 | |
| SCHEMBL24031267 | 0.85 | AR (0.71) | ARHDAC8HDAC6PGRS1PR3 | |
| SCHEMBL26801765 | 0.82 | AR (0.74) | ARPGRS1PR3CYP2C9CYP2D6 | |
| SCHEMBL25898091 | 0.82 | AR (0.66) | ARPGR | |
| SCHEMBL27295127 | 0.82 | AR (0.73) | ARHDAC8HDAC6PGRCYP2C9 | |
| SCHEMBL24031259 | 0.80 | AR (0.63) | ARS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2023-07-27 | — | — | US | disclosed |
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | AR, SHBG, CYP19A1 | AR 1/4885HDAC8 2474/4885HDAC6 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.