Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5416211 | 0.86 | CYP2A6 (0.34) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL4838080 | 0.82 | SLC6A4 (0.32) | ALDH1A1CYP2A6CYP1A2CYP2D6 | |
| SCHEMBL1134113 | 0.81 | ALDH1A1 (0.42) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL795439 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL30516319 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL5909814 | 0.77 | ALDH1A1 (0.39) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL6609964 | 0.74 | ACHE (0.37) | TSHR | |
| SCHEMBL2900789 | 0.73 | CA1 (0.35) | ALDH1A1CYP1A2KEAP1 | |
| SCHEMBL10953327 | 0.70 | NR4A1 (0.38) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 | |
| SCHEMBL11296618 | 0.70 | NR4A1 (0.38) | ALDH1A1CYP2A6TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288997-B1 | ADHESIVE COMPOSITIONS | POWDERTECH BICESTER LTD (GB) | 2020-12-30 | — | — | EP | disclosed |
| US-10689547-B2 | Adhesive compositions | POWDERTECH (BICESTER) LIMITED (GB) | 2020-06-23 | — | — | US | disclosed |
| US-20180355214-A1 | ADHESIVE COMPOSITIONS | POWDERTECH (BICESTER) LIMITED (GB) | 2018-12-13 | — | — | US | disclosed |
| EP-3288997-A1 | ADHESIVE COMPOSITIONS | Powdertech (Bicester) Limited (GB) | 2018-03-07 | — | — | EP | disclosed |
| WO-2016174469-A1 | ADHESIVE COMPOSITIONS | POWDERTECH (BICESTER) LIMITED (GB) | 2016-11-03 | — | — | WO | disclosed |
| US-8048981-B2 | Thermally curable compositions and method | GENERAL ELECTRIC COMPANY (US) | 2011-11-01 | — | — | US | disclosed |
| US-20080051553-A1 | Thermally curable compositions and method | GENERAL ELECTRIC COMPANY | 2008-02-28 | — | — | US | disclosed |
| US-6613437-B1 | Two-component preparations comprising components (I) and (II), wherein at least one component comprises epoxy compounds and the preparations cure by cationic polymerization, initiated by Lewis and/or Bronsted acids, after mixing of the two | 3M ESPE AG (DE) | 2003-09-02 | — | — | US | disclosed |
| US-6084004-A | MIXTURES OF EPOXY COMPOUNDS, DIARYLIODINIUM COMPOUNDS, ALPHA-DICARBONYL COMPOUNDS, AROMATIC AMINES, FILLERS AND ADJUVANTS WHICH POLYMERIZE TO YIELD STRONG TRANSPARENT PLASTICS FOR DENTAL PROSTHETICS | ESPE DENTAL AG (DE) | 2000-07-04 | — | — | US | disclosed |