⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14354842 | 0.83 | ALDH1A1 (0.41) | — | |
| SCHEMBL235146 | 0.79 | — | — | |
| SCHEMBL29536539 | 0.79 | — | — | |
| SCHEMBL30319978 | 0.76 | KDM4E (0.38) | — | |
| SCHEMBL2301288 | 0.76 | KDM4E (0.38) | — | |
| SCHEMBL1647418 | 0.76 | ALDH1A1 (0.50) | — | |
| SCHEMBL29977462 | 0.76 | ALDH1A1 (0.50) | — | |
| SCHEMBL31700841 | 0.76 | NOS3 (0.34) | — | |
| SCHEMBL28696981 | 0.76 | KMT2A (0.39) | — | |
| SCHEMBL9827479 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |