Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060197 | 0.81 | NUDT1 (0.49) | NUDT1BACE1HSP90AA1CACNA1BCYP1A2 | |
| SCHEMBL29458615 | 0.81 | ESR1 (0.49) | NUDT1BACE1HSP90AA1CACNA1BCYP1A2 | |
| SCHEMBL13609943 | 0.81 | NUDT1 (0.46) | NUDT1BACE1HSP90AA1CACNA1BMEN1 | |
| SCHEMBL2340495 | 0.81 | ESR1 (0.49) | NUDT1BACE1HSP90AA1CACNA1BCYP1A2 | |
| SCHEMBL2913464 | 0.81 | NUDT1 (0.44) | NUDT1BACE1HSP90AA1CACNA1BCYP1A2 | |
| SCHEMBL10596142 | 0.80 | CNR1 (0.56) | NUDT1BACE1HSP90AA1CYP1A2CNR1 | |
| SCHEMBL20717757 | 0.79 | ESR1 (0.50) | NUDT1BACE1HSP90AA1CACNA1BCYP1A2 | |
| SCHEMBL3680857 | 0.78 | ESR1 (0.54) | MEN1KMT2AESR1ESR2ALDH1A1 | |
| SCHEMBL30994345 | 0.78 | ESR1 (0.54) | MEN1KMT2AESR1ESR2ALDH1A1 | |
| SCHEMBL29499839 | 0.78 | ESR1 (0.54) | MEN1KMT2AESR1ESR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234905-A1 | NOVEL TRISPHENOL DERIVATIVE | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2023-07-27 | — | — | US | disclosed |
| US-20230234905-A1 | NOVEL TRISPHENOL DERIVATIVE | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234905-A1 | NOVEL TRISPHENOL DERIVATIVE | TTPA, CDK2AP2, CDKL2 | NUDT1 2727/4885BACE1 4376/4885HSP90AA1 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.