Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.34 |
| ▸ | TNF | P01375 | 5/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30550902 | 0.82 | TNF (0.37) | TIPARPTNFPSMB1PSMB5HDAC3 | |
| SCHEMBL25320565 | 0.82 | TNF (0.37) | TIPARPTNFPSMB1PSMB5HDAC3 | |
| SCHEMBL25320560 | 0.82 | TNF (0.37) | TIPARPTNFPSMB1PSMB5HDAC3 | |
| SCHEMBL25321729 | 0.81 | TNF (0.43) | TIPARPTNFPSMB1PSMB5HDAC3 | |
| SCHEMBL25324896 | 0.80 | PSMB1 (0.41) | TIPARPTNFPSMB1PSMB5HDAC3 | |
| SCHEMBL25898500 | 0.80 | TIPARP (0.34) | TIPARPTNFHDAC3HDAC1HDAC6 | |
| SCHEMBL30550904 | 0.79 | TIPARP (0.39) | TIPARPTNFPSMB1PSMB5HDAC3 | |
| SCHEMBL25319089 | 0.79 | TIPARP (0.39) | TIPARPTNFPSMB1PSMB5HDAC3 | |
| SCHEMBL25319081 | 0.79 | TIPARP (0.39) | TIPARPTNFPSMB1PSMB5HDAC3 | |
| SCHEMBL25323234 | 0.78 | TIPARP (0.48) | TIPARPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |