Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 4/20 | 0.39 |
| ▸ | TNF | P01375 | 8/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25319089 | 1.00 | TIPARP (0.39) | TIPARPTNFHDAC3HDAC1HDAC6 | |
| SCHEMBL25319081 | 1.00 | TIPARP (0.39) | TIPARPTNFHDAC3HDAC1HDAC6 | |
| SCHEMBL30550902 | 0.85 | TNF (0.37) | TIPARPTNFHDAC3HDAC1HDAC6 | |
| SCHEMBL25320565 | 0.85 | TNF (0.37) | TIPARPTNFHDAC3HDAC1HDAC6 | |
| SCHEMBL25320560 | 0.85 | TNF (0.37) | TIPARPTNFHDAC3HDAC1HDAC6 | |
| SCHEMBL31362983 | 0.83 | TIPARP (0.42) | TIPARPTNFHDAC3HDAC1HDAC6 | |
| SCHEMBL25320536 | 0.80 | TIPARP (0.40) | TIPARPTNFHDAC3HDAC1HDAC6 | |
| SCHEMBL25320533 | 0.80 | TIPARP (0.40) | TIPARPTNFHDAC3HDAC1HDAC6 | |
| SCHEMBL25898499 | 0.79 | TIPARP (0.34) | TIPARPTNFHDAC3HDAC1HDAC6 | |
| SCHEMBL25324896 | 0.78 | PSMB1 (0.41) | TIPARPTNFHDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4469448-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118591537-A | PARP7 inhibitors | 吉利德科学公司 | 2024-09-03 | — | — | CN | disclosed |
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |