Sugi Predict

Sugi Predict / Compounds / SCHEMBL258986

SCHEMBL258986

SCHEMBL258986

O=C(O)CCC(=O)N(CCCNC(=O)OCC1c2ccccc2-c2ccccc21)CCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.71
▸ HTT P42858 1/20 0.43
▸ EPHX2 P34913 1/20 0.43
▸ OPRD1 P41143 1/20 0.42
▸ CASP3 P42574 2/20 0.41
▸ DOT1L Q8TEK3 1/20 0.41
▸ FABP7 O15540 1/20 0.40
▸ FABP5 Q01469 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10284512 0.93 KMT2A (0.67) KMT2AHTTEPHX2OPRD1CASP3
SCHEMBL31004973 0.93 KMT2A (0.67) KMT2AHTTEPHX2OPRD1CASP3
SCHEMBL29792075 0.86 KMT2A (0.90) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL29370234 0.86 KMT2A (0.90) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL178801 0.86 KMT2A (0.90) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL30678094 0.85 KMT2A (0.59) KMT2AEPHX2OPRD1CASP3DOT1L
SCHEMBL22799181 0.85 KMT2A (0.57) KMT2AEPHX2OPRD1CASP3FABP7
SCHEMBL31230162 0.85 KMT2A (0.57) KMT2AEPHX2OPRD1CASP3FABP7
Water SCHEMBL21809392 0.85 KMT2A (0.88) KMT2AHTTEPHX2CASP3FABP7
SCHEMBL29482640 0.85 KMT2A (0.97) KMT2AHTTEPHX2CASP3FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133985-B2 Peptide nucleic acids conjugated with multi-amine linkers and nucleic acid detecting device using the same PANAGENE INC. (KR) 2012-03-13 — — US disclosed
US-8133985-B2 Peptide nucleic acids conjugated with multi-amine linkers and nucleic acid detecting device using the same PANAGENE INC. (KR) 2012-03-13 — — US disclosed
US-8133985-B2 Peptide nucleic acids conjugated with multi-amine linkers and nucleic acid detecting device using the same PANAGENE INC. (KR) 2012-03-13 — — US disclosed
US-20090312197-A1 PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME PANAGENE INC. (KR) 2009-12-17 — — US disclosed
US-20090312197-A1 PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME PANAGENE INC. (KR) 2009-12-17 — — US disclosed
US-20090312197-A1 PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME PANAGENE INC. (KR) 2009-12-17 — — US disclosed
WO-2008072933-A1 PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI -AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME PANAGENE INC. (KR) 2008-06-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090312197-A1 PEPTIDE NUCLEIC ACIDS CONJUGATED WITH MULTI-AMINE LINKERS AND NUCLEIC ACID DETECTING DEVICE USING THE SAME NPPA, PARN, PARG KMT2A 548/4885HTT 3006/4885EPHX2 3887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.