Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046325 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL1046324 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL27389278 | 0.83 | ACACB (0.38) | ALDH1A1MAPTLMNAMAPK1KDM4E | |
| SCHEMBL15542521 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL25898740 | 0.79 | MAPT (0.32) | MAPTACACB | |
| SCHEMBL30279208 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL12983104 | 0.77 | MAPT (0.53) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL13370661 | 0.76 | HTT (0.54) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL16671146 | 0.76 | HTT (0.54) | ALDH1A1MAPTGFERLMNAMAPK1 | |
| SCHEMBL3567265 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MAPTGFERLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138362-A1 | WEE1 INHIBITOR, PREPARATION THEREFOR, AND USE THEREOF | 江苏天士力帝益药业有限公司 | 2023-07-27 | — | — | WO | disclosed |