Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25900778 | 0.84 | MEN1 (0.33) | — | |
| SCHEMBL25898689 | 0.79 | ALDH1A1 (0.48) | MAPTACACB | |
| SCHEMBL236762 | 0.79 | KDM4E (0.35) | MAPT | |
| SCHEMBL4706606 | 0.76 | MAOA (0.33) | MAPT | |
| SCHEMBL239087 | 0.74 | MAOA (0.32) | MAPTACACB | |
| SCHEMBL238837 | 0.74 | MAOA (0.32) | MAPTACACB | |
| SCHEMBL29209046 | 0.74 | KDM4E (0.46) | MAPT | |
| SCHEMBL240100 | 0.74 | KDM4E (0.46) | MAPT | |
| SCHEMBL5282437 | 0.74 | ACACB (0.36) | ACACBKCNH2 | |
| SCHEMBL3563045 | 0.74 | SCN9A (0.38) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138362-A1 | WEE1 INHIBITOR, PREPARATION THEREFOR, AND USE THEREOF | 江苏天士力帝益药业有限公司 | 2023-07-27 | — | — | WO | disclosed |