Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 18/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25898794 | 0.88 | TIPARP (0.42) | GRM2TIPARPKDM4ELMNAMAPT | |
| SCHEMBL25898823 | 0.88 | GRM2 (0.37) | GRM2 | |
| SCHEMBL26786739 | 0.85 | GRM2 (0.36) | GRM2KDM4ELMNAMAPTHTT | |
| SCHEMBL25898407 | 0.84 | TIPARP (0.48) | GRM2TIPARP | |
| SCHEMBL25898806 | 0.84 | LMNA (0.40) | GRM2KDM4ELMNAMAPTHTT | |
| SCHEMBL25898816 | 0.80 | GRM2 (0.38) | GRM2TIPARP | |
| SCHEMBL25898801 | 0.79 | GRM2 (0.40) | GRM2KDM4ELMNAMAPTHTT | |
| SCHEMBL26786770 | 0.79 | GRM2 (0.37) | GRM2KDM4ELMNAMAPTHTT | |
| SCHEMBL25900019 | 0.79 | GRM2 (0.35) | GRM2KDM4ELMNAMAPTHTT | |
| SCHEMBL25900007 | 0.79 | TIPARP (0.37) | GRM2TIPARPKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |