Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 11/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25899203 | 0.89 | TLR8 (0.37) | TIPARPGRM2KDM4ELMNAMAPT | |
| SCHEMBL25898794 | 0.86 | TIPARP (0.42) | TIPARPGRM2KDM4ELMNAMAPT | |
| SCHEMBL25899251 | 0.86 | TIPARP (0.46) | TIPARPGRM2KDM4ELMNAMAPT | |
| SCHEMBL25899963 | 0.86 | GRM2 (0.41) | TIPARPGRM2TLR8 | |
| SCHEMBL25899977 | 0.85 | HSD17B10 (0.40) | TIPARPGRM2KDM4EHTT | |
| SCHEMBL25900019 | 0.85 | GRM2 (0.35) | GRM2KDM4ELMNAMAPTHTT | |
| SCHEMBL25899908 | 0.85 | TIPARP (0.51) | TIPARPGRM2KDM4ESMN1; SMN2TLR8 | |
| SCHEMBL25898801 | 0.84 | GRM2 (0.40) | GRM2KDM4ELMNAMAPTHTT | |
| SCHEMBL25898816 | 0.82 | GRM2 (0.38) | TIPARPGRM2 | |
| SCHEMBL25898093 | 0.81 | LMNA (0.41) | TIPARPGRM2KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |