SCHEMBL4367549

SCHEMBL4367549

CCCCN(c1ccccc1)c1ccc(-c2ccc(N(CCCC)c3ccccc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
CASP1 P29466 1/20 0.47
BRCA1 P38398 1/20 0.47
CASP7 P55210 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HSD17B10 Q99714 1/20 0.47
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
HTT P42858 2/20 0.46
ALDH1A1 P00352 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALOX5 P09917 3/20 0.44
DHFR P00374 2/20 0.44
CYP1A2 P05177 1/20 0.43
LMNA P02545 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
SIGMAR1 Q99720 1/20 0.41
MTNR1A P48039 1/20 0.41
MTNR1B P49286 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11232618 0.92 NPC1 (0.47) MEN1KMT2ACASP1BRCA1CASP7
SCHEMBL2589900 0.92 MEN1 (0.51) MEN1KMT2ACASP1BRCA1CASP7
SCHEMBL157807 0.92 MEN1 (0.51) MEN1KMT2ACASP1BRCA1CASP7
Bromide SCHEMBL10687133 0.90 MEN1 (0.50) MEN1KMT2ACASP1BRCA1CASP7
SCHEMBL7151745 0.88 MTNR1A (0.43) SMN1; SMN2GAAHPGDHTTALDH1A1
SCHEMBL12669219 0.87 HSD11B1 (0.47) GAAHPGDSIGMAR1LTB4R2KCNH2
SCHEMBL17660041 0.86 DHFR (0.46) MEN1KMT2ACASP1BRCA1CASP7
SCHEMBL10473072 0.86 DHFR (0.46) MEN1KMT2ACASP1BRCA1CASP7
SCHEMBL17431103 0.86 CNR2 (0.47) MEN1KMT2ACASP1BRCA1CASP7
SCHEMBL5713305 0.86 ALDH1A1 (0.48) MEN1KMT2ACASP1BRCA1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090075190-A1 Imaging member having a dual charge generation layer XEROX CORPORATION (US) 2009-03-19 US claimed
US-6294300-B1 HOLE TRANSPORT COMPONENT IS N,N'-DIPHENYL-N,N'-BIS(3-METHYLPROPYL)-(1,1'-BIPHENYL)-4,4'-DI AMINE; THAT FORMS A CONCENTRATION GRADIENT IN THE CHARGE GENERATING LAYER XEROX CORPORATION 2001-09-25 US claimed
EP-2759574-B1 CHARGE-TRANSPORTING VARNISH NISSAN CHEMICAL CORP (JP) 2019-08-21 EP disclosed
US-9444052-B2 Charge-transporting varnish NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-09-13 US disclosed
US-9444052-B2 Charge-transporting varnish NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-09-13 US disclosed
US-9444052-B2 Charge-transporting varnish NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-09-13 US disclosed
US-20140227815-A1 CHARGE-TRANSPORTING VARNISH NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-08-14 US disclosed
US-20140227815-A1 CHARGE-TRANSPORTING VARNISH NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-08-14 US disclosed
US-20140227815-A1 CHARGE-TRANSPORTING VARNISH NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-08-14 US disclosed
EP-2759574-A1 CHARGE-TRANSPORTING VARNISH Nissan Chemical Industries, Ltd. (JP) 2014-07-30 EP disclosed
WO-2013042623-A1 CHARGE-TRANSPORTING VARNISH 日産化学工業株式会社 (JP) 2013-03-28 WO disclosed
US-7476479-B2 Hydrolyzed semi-conductive nanoparticles for imaging member undercoating layers XEROX CORPORATION (US) 2009-01-13 US disclosed
US-7309551-B2 Electron conductive overcoat layer for photoreceptors XEROX CORPORATION (US) 2007-12-18 US disclosed
US-20060204872-A1 Hydrolyzed semi-conductive nanoparticles for imaging member undercoating layers XEROX CORPORATION (US) 2006-09-14 US disclosed
US-20060204873-A1 Electron conductive overcoat layer for photoreceptors XEROX CORPORATION (US) 2006-09-14 US disclosed
US-6300027-B1 Low surface energy photoreceptors XEROX CORPORATION 2001-10-09 US disclosed
US-6294300-B1 HOLE TRANSPORT COMPONENT IS N,N'-DIPHENYL-N,N'-BIS(3-METHYLPROPYL)-(1,1'-BIPHENYL)-4,4'-DI AMINE; THAT FORMS A CONCENTRATION GRADIENT IN THE CHARGE GENERATING LAYER XEROX CORPORATION 2001-09-25 US disclosed
US-6180309-B1 Organic photoreceptor with improved adhesion between coated layers XEROX CORPORATION 2001-01-30 US disclosed
US-6165660-A Organic photoreceptor with improved adhesion between coated layers XEROX CORPORATION (US) 2000-12-26 US disclosed
US-5164276-A Amine dopants, electrography XEROX CORPORATION (US) 1992-11-17 US disclosed