⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16891527 | 0.75 | — | — | |
| SCHEMBL16417580 | 0.70 | — | — | |
| SCHEMBL15935261 | 0.70 | — | — | |
| SCHEMBL23486197 | 0.67 | MAPK9 (0.33) | — | |
| SCHEMBL18238975 | 0.67 | PIM2 (0.32) | — | |
| SCHEMBL18237755 | 0.65 | — | — | |
| SCHEMBL12702744 | 0.64 | LMNA (0.40) | — | |
| SCHEMBL12702868 | 0.63 | — | — | |
| SCHEMBL16746122 | 0.63 | SLC40A1 (0.33) | — | |
| SCHEMBL18238939 | 0.60 | NPC1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |