SCHEMBL258994

SCHEMBL258994

N#CC=CC=Cc1ccccc1.[Si]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.61
LMNA P02545 3/20 0.46
MAPK1 P28482 2/20 0.46
ALDH1A1 P00352 2/20 0.46
TRPA1 O75762 2/20 0.46
ALOX5 P09917 1/20 0.46
MCL1 Q07820 1/20 0.43
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
MAPT P10636 2/20 0.39
NPC1 O15118 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17741 0.98 MAOB (0.64) MAOBLMNAMAPK1ALDH1A1TRPA1
Benzene SCHEMBL28245201 0.98 MAOB (0.64) MAOBLMNAMAPK1ALDH1A1TRPA1
SCHEMBL679380 0.98 MAOB (0.64) MAOBLMNAMAPK1ALDH1A1TRPA1
SCHEMBL29566168 0.96 MAOB (0.61) MAOBLMNAMAPK1ALDH1A1TRPA1
Hydrochloric Acid SCHEMBL11079362 0.96 MAOB (0.61) MAOBLMNAMAPK1ALDH1A1TRPA1
Ethylene SCHEMBL7925748 0.94 MAOB (0.58) MAOBLMNAMAPK1ALDH1A1TRPA1
SCHEMBL30645565 0.94 MAOB (0.58) MAOBLMNAMAPK1ALDH1A1TRPA1
SCHEMBL27491941 0.92 MAOB (0.56) MAOBLMNAMAPK1ALDH1A1TRPA1
Butadiene SCHEMBL116599 0.90 MAOB (0.54) MAOBLMNAMAPK1ALDH1A1TRPA1
Bicarbonate SCHEMBL16751853 0.90 MAOB (0.54) MAOBLMNAMAPK1ALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113416322-B Preparation method and application of polycarbonate low-temperature toughening master batch with compatibilization function 常州大学 2022-03-04 CN claimed
CN-113416322-A Preparation method and application of polycarbonate low-temperature toughening master batch with compatibilization function 常州大学 2021-09-21 CN claimed
US-20090042736-A1 Biochip and process for the production of a biochip DSM IP ASSETS B.V. (NL) 2009-02-12 US claimed
EP-1877533-A2 BIOCHIP AND PROCESS FOR THE PRODUCTION OF A BIOCHIP DSM IP ASSETS B.V. (NL) 2008-01-16 EP claimed
WO-2006112709-A2 BIOCHIP AND PROCESS FOR THE PRODUCTION OF A BIOCHIP DSM IP ASSETS B.V. (NL) 2006-10-26 WO claimed
US-20240075266-A1 Microneedle Array Device, Methods Of Manufacturing And Use Thereof NanoCav, LLC 2024-03-07 US disclosed
US-20240075267-A1 Microneedle Array Device, Methods Of Manufacturing And Use Thereof NanoCav, LLC 2024-03-07 US disclosed
CN-113416322-B Preparation method and application of polycarbonate low-temperature toughening master batch with compatibilization function 常州大学 2022-03-04 CN disclosed
CN-113416322-B Preparation method and application of polycarbonate low-temperature toughening master batch with compatibilization function 常州大学 2022-03-04 CN disclosed
CN-113416322-A Preparation method and application of polycarbonate low-temperature toughening master batch with compatibilization function 常州大学 2021-09-21 CN disclosed
CN-113416322-A Preparation method and application of polycarbonate low-temperature toughening master batch with compatibilization function 常州大学 2021-09-21 CN disclosed
US-20210170151-A1 Microneedle Array Device, Methods Of Manufacture And Use Thereof NanoCav, LLC 2021-06-10 US disclosed
EP-1133574-A1 METHODS AND APPARATUS FOR FLOW-THROUGH HYBRIDIZATION THE PERKIN-ELMER CORPORATION (US) 2001-09-19 EP disclosed
US-6268210-B1 Sandwich arrays of biological compounds HYSEQ, INC. 2001-07-31 US disclosed
US-6245518-B1 SPATIALLY-ADDRESSABLE ARRAY OF COMPOUNDS; AMOUNT OF TRACER MOIETY ATTACHED TO ADDRESS IS PROPORTIONAL TO AMOUNT OF COMPOUNDS ATTACHED THERE; MORE ACCURATE ANALYSIS HYSEQ, INC. 2001-06-12 US disclosed
WO-2000040334-A1 FIBER ARRAY FOR CONTACTING CHEMICAL SPECIES AND METHODS FOR USING AND MAKING SAME PE CORPORATION (NY) (US) 2000-07-13 WO disclosed
WO-2000034523-A1 POLYNUCLEOTIDE ARRAYS AND METHODS OF MAKING AND USING THE SAME HYSEQ, INC. (US) 2000-06-15 WO disclosed
WO-2000031304-A1 METHODS AND APPARATUS FOR FLOW-THROUGH HYBRIDIZATION THE PERKIN-ELMER CORPORATION (US) 2000-06-02 WO disclosed
WO-1999061461-A1 SANDWICH ARRAYS AND METHODS OF MAKING AND USING THE SAME HYSEQ, INC. (US) 1999-12-02 WO disclosed
WO-1999060170-A1 LINEAR ARRAYS OF IMMOBILIZED COMPOUNDS AND METHODS OF USING SAME HYSEQ, INC. (US) 1999-11-25 WO disclosed