SCHEMBL679380

SCHEMBL679380

N#C/C=C/C=C/c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.64
LMNA P02545 3/20 0.48
MAPK1 P28482 2/20 0.48
ALDH1A1 P00352 2/20 0.48
TRPA1 O75762 1/20 0.48
ALOX5 P09917 1/20 0.48
MCL1 Q07820 2/20 0.44
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
MAPT P10636 2/20 0.41
NPC1 O15118 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28245201 1.00 MAOB (0.64) MAOBLMNAMAPK1ALDH1A1TRPA1
SCHEMBL17741 1.00 MAOB (0.64) MAOBLMNAMAPK1ALDH1A1TRPA1
SCHEMBL29566168 0.98 MAOB (0.61) MAOBLMNAMAPK1ALDH1A1TRPA1
Hydrochloric Acid SCHEMBL11079362 0.98 MAOB (0.61) MAOBLMNAMAPK1ALDH1A1TRPA1
SCHEMBL258994 0.98 MAOB (0.61) MAOBLMNAMAPK1ALDH1A1TRPA1
SCHEMBL30645565 0.96 MAOB (0.58) MAOBLMNAMAPK1ALDH1A1TRPA1
Ethylene SCHEMBL7925748 0.96 MAOB (0.58) MAOBLMNAMAPK1ALDH1A1TRPA1
SCHEMBL27491941 0.94 MAOB (0.56) MAOBLMNAMAPK1ALDH1A1TRPA1
Bicarbonate SCHEMBL16751853 0.92 MAOB (0.54) MAOBLMNAMAPK1ALDH1A1TRPA1
Butadiene SCHEMBL116599 0.92 MAOB (0.54) MAOBLMNAMAPK1ALDH1A1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101885816-B Method for preparing poly(styrene-b-acrylonitrile) by two-step polymerization method UNIV NORTHWESTERN POLYTECHNIC 2012-02-15 CN disclosed
CN-101885816-B Method for preparing poly(styrene-b-acrylonitrile) by two-step polymerization method UNIV NORTHWESTERN POLYTECHNIC 2012-02-15 CN disclosed
US-20110275774-A1 ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER YAMAGO SHIGERU 2011-11-10 US disclosed
US-8008414-B2 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
EP-1767539-B1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL CO LTD (JP) 2011-07-27 EP disclosed
US-20110060107-A1 PREPARATION OF FUNCTIONAL POLYMERS CARNEGIE MELLON UNIVERSITY (US) 2011-03-10 US disclosed
CN-101885816-A Method for preparing poly(styrene-b-acrylonitrile) by two-step polymerization method UNIV NORTHWESTERN POLYTECHNIC 2010-11-17 CN disclosed
CN-101885816-A Method for preparing poly(styrene-b-acrylonitrile) by two-step polymerization method UNIV NORTHWESTERN POLYTECHNIC 2010-11-17 CN disclosed
US-7795355-B2 Preparation of functional polymers CARNEGIE MELLON UNIVERSITY (US) 2010-09-14 US disclosed
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
US-20070244265-A1 Preparation of Functional Polymers CARNEGIE MELLON UNIVERSITY 2007-10-18 US disclosed
EP-1767539-A1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL COMPANY, LTD. (JP) 2007-03-28 EP disclosed
WO-2005087818-A1 PREPARATION OF FUNCTIONAL POLYMERS CARNEGIE MELLON UNIVERSITY (US) 2005-09-22 WO disclosed
US-4031290-A ALPHA-BETA MONOMERS, CATALYSIS PPG INDUSTRIES, INC. (US) 1977-06-21 US disclosed
US-4016332-A OF ETHYLENICALLY UNSATURATED MONOMERS PPG INDUSTRIES, INC. (US) 1977-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer AOC2, ODC1, MCM7 MAOB 156/4885LMNA 1912/4885MAPK1 493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.