Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TGM1 | P22735 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1199630 | 0.90 | GPR119 (0.50) | GPR119HSD11B1PARP1HDAC1F13A1 | |
| SCHEMBL15441789 | 0.90 | GPR119 (0.53) | GPR119HSD11B1PARP1HDAC1F13A1 | |
| SCHEMBL30261871 | 0.90 | GPR119 (0.53) | GPR119HSD11B1PARP1HDAC1F13A1 | |
| SCHEMBL1199627 | 0.90 | GPR119 (0.50) | GPR119HSD11B1PARP1HDAC1F13A1 | |
| SCHEMBL1199629 | 0.90 | GPR119 (0.50) | GPR119HSD11B1PARP1HDAC1F13A1 | |
| SCHEMBL23551511 | 0.90 | GPR119 (0.50) | GPR119HSD11B1PARP1HDAC1F13A1 | |
| SCHEMBL2883317 | 0.88 | HDAC1 (0.50) | GPR119HSD11B1PARP1HDAC1F13A1 | |
| SCHEMBL12194099 | 0.88 | GPR119 (0.49) | GPR119HSD11B1PARP1HDAC1F13A1 | |
| SCHEMBL24989562 | 0.88 | FAAH (0.52) | GPR119HSD11B1PARP1HDAC1F13A1 | |
| SCHEMBL2069447 | 0.88 | GPR119 (0.49) | GPR119HSD11B1PARP1HDAC1F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138362-A1 | WEE1 INHIBITOR, PREPARATION THEREFOR, AND USE THEREOF | 江苏天士力帝益药业有限公司 | 2023-07-27 | — | — | WO | disclosed |