Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.57 |
| ▸ | AR | P10275 | 7/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25902429 | 0.94 | AR (0.62) | CRBNARDDB1HPGDSALDH1A1 | |
| SCHEMBL25902442 | 0.94 | AR (0.62) | CRBNARDDB1HPGDSALDH1A1 | |
| SCHEMBL25902455 | 0.94 | AR (0.62) | CRBNARDDB1HPGDSALDH1A1 | |
| SCHEMBL25899997 | 0.94 | AR (0.62) | CRBNARDDB1HPGDSALDH1A1 | |
| SCHEMBL25902416 | 0.93 | AR (0.63) | CRBNARDDB1HPGDS | |
| SCHEMBL25902377 | 0.89 | CRBN (0.64) | CRBNARDDB1HPGDSALDH1A1 | |
| SCHEMBL25899979 | 0.88 | AR (0.67) | CRBNARDDB1HPGDSALDH1A1 | |
| SCHEMBL24031698 | 0.87 | AR (0.53) | CRBNARDDB1HPGDSALDH1A1 | |
| SCHEMBL25899944 | 0.85 | CRBN (0.60) | CRBNARDDB1HPGDS | |
| SCHEMBL26818516 | 0.84 | AR (0.54) | CRBNARDDB1HPGDSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | AR, SHBG, CYP19A1 | CRBN 945/4885AR 1/4885DDB1 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.