Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.60 |
| ▸ | AR | P10275 | 7/20 | 0.60 |
| ▸ | HPGDS | O60760 | 2/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.44 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
| ▸ | IRAK3 | Q9Y616 | 2/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.42 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.42 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25899959 | 0.95 | AR (0.63) | CRBNARHPGDSDDB1IRAK1 | |
| SCHEMBL25902416 | 0.92 | AR (0.63) | CRBNARHPGDSDDB1IRAK1 | |
| SCHEMBL25902429 | 0.91 | AR (0.62) | CRBNARHPGDSDDB1IRAK1 | |
| SCHEMBL25902455 | 0.91 | AR (0.62) | CRBNARHPGDSDDB1IRAK1 | |
| SCHEMBL25902442 | 0.91 | AR (0.62) | CRBNARHPGDSDDB1IRAK1 | |
| SCHEMBL25899997 | 0.91 | AR (0.62) | CRBNARHPGDSDDB1IRAK1 | |
| SCHEMBL25899919 | 0.89 | CRBN (0.61) | CRBNARHPGDSDDB1IRAK1 | |
| SCHEMBL25899979 | 0.86 | AR (0.67) | CRBNARHPGDSDDB1 | |
| SCHEMBL25899735 | 0.85 | CRBN (0.57) | CRBNARHPGDSDDB1 | |
| SCHEMBL25900824 | 0.85 | CRBN (0.68) | CRBNARHPGDSDDB1IRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233690-A1 | ANDROGEN RECEPTOR PROTEIN DEGRADERS | AR, SHBG, CYP19A1 | CRBN 945/4885AR 1/4885HPGDS 3551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.