Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440358 | 1.00 | KDM4E (0.45) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL25318719 | 0.85 | MAPT (0.51) | KDM4EMAPTALDH1A1GAAMTNR1A | |
| SCHEMBL30439531 | 0.85 | MTNR1A (0.48) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL25899800 | 0.85 | MTNR1A (0.48) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL25899798 | 0.84 | MTNR1B (0.44) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL30439373 | 0.84 | MTNR1B (0.44) | KDM4EMAPTALDH1A1HPGDGLA | |
| SCHEMBL30439947 | 0.78 | MTNR1A (0.60) | KDM4EMAPTALDH1A1GAAMTNR1A | |
| SCHEMBL25899795 | 0.78 | MTNR1A (0.60) | KDM4EMAPTALDH1A1GAAMTNR1A | |
| SCHEMBL30439647 | 0.76 | TP53 (0.41) | MAPTGAADYRK1AMTNR1AMTNR1B | |
| SCHEMBL25317235 | 0.76 | TP53 (0.41) | MAPTGAADYRK1AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114858-A1 | BENZOFURAN AND BENZOTHIOPHENE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |