Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | MEN1 | O00255 | 7/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | POLB | P06746 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18988717 | 0.83 | STAT3 (0.43) | STAT3ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15173341 | 0.81 | MAPK1 (0.46) | STAT3ALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL20344472 | 0.80 | STAT3 (0.33) | STAT3ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL23652392 | 0.80 | MEN1 (0.37) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL25900006 | 0.79 | KDM4E (0.45) | STAT3ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL23891902 | 0.76 | AOC1 (0.34) | GAA | |
| SCHEMBL16011566 | 0.76 | FFAR4 (0.36) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL8161597 | 0.76 | SMN1; SMN2 (0.37) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL21317859 | 0.76 | AOC1 (0.43) | STAT3MAPK1 | |
| SCHEMBL28879850 | 0.75 | HSP90AA1 (0.41) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |