Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.32 |
| ▸ | POLB | P06746 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25899811 | 0.80 | STAT3 (0.35) | STAT3MEN1ALDH1A1KMT2APOLB | |
| SCHEMBL10407956 | 0.79 | POLB (0.39) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL19980140 | 0.78 | KIF11 (0.40) | MEN1KMT2APOLBMAPTGAA | |
| SCHEMBL19980152 | 0.77 | TMEM97 (0.38) | ALDH1A1POLBMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL20615440 | 0.76 | CHRNB2 (0.41) | MEN1KMT2APOLBSMN1; SMN2LMNA | |
| SCHEMBL15173341 | 0.76 | MAPK1 (0.46) | STAT3ALDH1A1POLBMAPTKDM4E | |
| SCHEMBL19980141 | 0.75 | STAT3 (0.32) | STAT3MEN1ALDH1A1KMT2APOLB | |
| SCHEMBL19980155 | 0.75 | STAT3 (0.32) | STAT3MEN1ALDH1A1KMT2APOLB | |
| SCHEMBL20344614 | 0.75 | STAT3 (0.31) | STAT3MEN1ALDH1A1KMT2APOLB | |
| SCHEMBL21983696 | 0.73 | APEX1 (0.38) | STAT3MEN1ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342771-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2018-07-04 | — | — | EP | disclosed |