Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.50 |
| ▸ | TNF | P01375 | 8/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25900150 | 0.93 | TIPARP (0.48) | TIPARPTNFPSMB5PSMB2GRM2 | |
| SCHEMBL25899897 | 0.89 | TIPARP (0.51) | TIPARPTNFGRM2TLR8 | |
| SCHEMBL25899908 | 0.86 | TIPARP (0.51) | TIPARPTNFGRM2TLR8 | |
| SCHEMBL25899853 | 0.85 | TIPARP (0.60) | TIPARPTNFCNR2GRM2TLR8 | |
| SCHEMBL25899963 | 0.85 | GRM2 (0.41) | TIPARPTNFCNR2GRM2TLR8 | |
| SCHEMBL26789113 | 0.84 | TIPARP (0.48) | TIPARPTNFGRM2TLR8 | |
| SCHEMBL26787748 | 0.84 | TIPARP (0.59) | TIPARPTNFCNR2GRM2TLR8 | |
| SCHEMBL25900490 | 0.84 | TIPARP (0.43) | TIPARPTNFPSMB5PSMB2GRM2 | |
| SCHEMBL25899110 | 0.84 | TIPARP (0.47) | TIPARPTNFGRM2TLR8 | |
| SCHEMBL25898391 | 0.83 | TIPARP (0.46) | TIPARPTNFGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |